With your help, we can help advance medical knowledge and improve the health and well-being of countless others.
Our goal is to assist the pharmaceutical and medical device industries develop new and effective products to treat a multitude of medical conditions and illnesses. We perform this important work through the administration of clinical trials.
Please consider joining us in this effort. Our experienced and professional clinical research staff are highly qualified and fully committed to engaging you and your primary care physician as informed partners in everything we do.
Inpatient Studies
See if you pre-qualify for any of the research studies we are now conducting in your area by following one of the links below.
If you have kidney disease, you many qualify for a study looking at new medications and/or therapies. Call us at 865-305-3784 or fill out the volunteer form below.
If you have liver disease, you many qualify for a study looking at new medications and/or therapies. Call us at 865-305-3784 or fill out the volunteer form below.
We are currently working on new research and development for Multiple Sclerosis treatment and therapies. For more information, please fill out the form below and a team member will reach out to you.
AMR Knoxville is conducting a clinical research study to evaluate the safety of the study drug in volunteers with varying levels of liver function.
Qualified participants:
· are ages 18 to 80
· must complete nine-day in-clinic stay with one follow-up phone call
· meet other study criteria
Receive all study-related care at no cost. Compensation is available up to $4,125.00 for time and travel. Insurance is not required. Contact AMR Knoxville at 865-305-DRUG (3784) today.
AMR Knoxville is conducting a clinical trial of an investigational medication for those with kidney disease.
Qualified participants must:
· be 18 to 75 years of age
· have mild to severe kidney disease but are considered in otherwise good health
· have a BMI between 18.0 to 42.0
· be able to complete six days/five nights in our research center as well as one follow-up visit
· meet other study criteria
Qualified participants will receive at no cost:
· all study-related care
· the investigational oral medication
Compensation may be available for eligible participants up to $2,725.00. Talk to one of our experienced recruitment specialists today by calling AMR Knoxville at 865-305-DRUG (3784).
AMR Knoxville is conducting a study testing different doses of an investigational medication for people who are overweight and have non-alcoholic fatty liver disease.
Qualified participants must:
· be ages 18 to 75
· be considered medically overweight or obese
· have non-alcoholic fatty liver disease (NASH)
· be willing to complete this 18-week study with 17 visits in our research center
· meet other study criteria
Receive all study-related care and the investigational medication or placebo at no cost. Compensation is available up to $6,950.00 for time and travel. Let AMR Knoxville see if you qualify! Call 865-305-DRUG (3784) today!
Have you considered volunteering for a clinical research study? If yes, Alliance for Multispecialty Research is enrolling adults with kidney disease for a clinical trial testing an investigational cancer medication.
Qualified participants:
· are ages 18 to 80
· must have moderate to severe kidney disease but are considered otherwise healthy
· meet other study criteria
Receive all study-related care at no cost. Compensation is available up to $2,770.00 for time and travel. Insurance is not required. Contact AMR Knoxville at 865-305-DRUG (3784) today.
Volunteers needed for a clinical study of an investigational therapy to improve glycemic control at AMR Knoxville. Qualified participants are ages 18 to 85 who have normal renal function and participants with renal impairment.
Qualified participants must:
· be 18 to 85 years of age
· have normal renal function or have renal impairment but are considered in otherwise good health
· be able to complete two(2) office visits and one (1) confinement period of up to six (6) days and five (5) nights
· meet other study criteria
Qualified participants will receive at no cost:
· all study-related care
· the investigational medication
Compensation up to $2,850.00 is available for time and travel. No insurance needed. Space is limited! Call AMR Knoxville at 865-305-DRUG (3784) or visit www.amrknoxville.com today.
Outpatient Studies
See if you pre-qualify for any of the research studies we are now conducting in your area by following one of the links below.
If you suffer from migraines, you may qualify for this study. We are evaluating an investigation oral medication to treat migraines in adults ages 18 – 65 years old. For more information, please fill out the form below and a team member will reach out to you.
If you or your loved ones suffer from frequent migraines, you know how debilitating they can be. Here at Alliance for Multispecialty Research we are evaluating an investigational oral treatment to prevent migraines in adults ages 18 and older. Those who qualify will have at least a 1-year migraine history and have taken an oral CGRP inhibitor in the last month and experienced an inadequate response to that treatment. The study involves 4 visits to the study center and compensation will be available up to $500 for your time & travel.
AMR Knoxville is currently seeking volunteers for an investigational medicine to potentially treat Celiac Disease.
Qualified participants must:
· be adults ages 18 to 65
· have been medically diagnosed with Celiac Disease
· be on strict GFD for at least 12 months
· have a previous biopsy to diagnosis CeD and have a copy of the report
· have had at most mild symptoms of Celiac Disease within the month before screening for this study
· meet other study criteria
Qualified participants will receive at no cost:
· all study-related medical exams and lab work
· investigational medicine or placebo
Compensation up to $2900 is available for time and travel. Medical insurance is not required.
AMR Knoxville is seeking volunteers for investigational gout clinical research studies.
Qualified participants must:
· be ages 18 to 85
· meet other study criteria
Qualified participants will receive at no cost:
· all study-related medical examinations and lab work
· the investigational medication
Compensation is available for time and travel. Insurance is not required. Contact AMR Knoxville at 865-305-3784 to learn more today!
AMR Knoxville is conducting a Clinical Trial of an Investigational Once-Daily ORAL Medication for Type 2 Diabetics with Cardiovascular Risk.
Qualified participants:
· Are 18 and Older
· Have either Heart Disease (incl. heart attack, stent, bypass surgery, heart failure, among others), Peripheral Artery Disease, Kidney Disease, or have had a Stroke or TIA
AND
· Have an A1C of 7 to 10.5 (Stable Treatment of One to Three Oral Medications for Diabetes) Note: If Taking Metformin, ≥1500 mg/day is required.
· Meet Other Study Requirements (Use of Insulin and/or Some Newer Injectable Diabetic Medications is Prohibited)
Reimbursement is available for time and travel. Contact AMR Knoxville at 865-305-3784.
AMR is currently accepting volunteers to participate in a high cholesterol clinical research study. Qualified participants are those ages 18 and older who meet other study criteria. Qualified participants will receive all study-related care and the investigational treatment or placebo at no cost. Compensation may be available up to $1,350.00 for study-related time and travel.
Cardiovascular disease is risky business! That’s why AMR Knoxville is conducting a clinical trial of an investigational medication to potentially reduce major adverse cardiovascular events in those with a previous history of adverse cardiovascular events and in those who are at high cardiovascular risk.
Qualified participants must:
· be ages 18 and older with a history of a major cardiovascular event Or
· be ages 50 and older who are at high risk for having their first major cardiovascular event
· meet other study criteria
Qualified participants will receive:
· all study-related care and the investigational medication or placebo at no cost
· compensation up to $2,550.00 for time and travel
Learn more by calling AMR Knoxville at 865-305-3784 today!
We have a pneumonia vaccine study coming up! If you’d like to see if you qualify and get on the waiting list, call us at 865-3053784 or fill out the volunteer form below.
AMR Knoxville is conducting a study to test an investigational drug on cardiovascular safety for people who are overweight or obese.
Qualified participants must:
· be ages 18 and older
· have a BMI of 27 or greater
· have cardiovascular disease, chronic kidney disease, or at least two risk factors for cardiovascular disease such as hypertension, dyslipidemia, Type 2 Diabetes, or Non-alcoholic steatohepatitis (NASH)
· meet other study criteria
Qualified participants will receive at no cost:
· all study-related care
· the investigational drug or placebo
Compensation for time and travel may be provided. Learn more by calling AMR Knoxville at 865-305-3784 today!
We have an RSV vaccine study coming up! If you’d like to see if you qualify and get on the waiting list, call us at 865-305-3784 or fill out the volunteer form below.
Are you considered medically obese and have Type 2 Diabetes? You may qualify for a clinical research study of an investigational daily oral medication at AMR Knoxville!
Qualified participants must:
· be 18 years of age or older
· have a history of at least one dietary effort to lose weight
· be diagnosed with Type 2 Diabetes
· must be considered over-weight or medically obese based on study requirements
· be able to complete the 22 study visits
· meet other study criteria
Qualified participants will receive at no cost:
· all study-related care
· the investigational daily oral medication or placebo
Compensation is available up to $2,716.00 for time and travel. Insurance is not required. Contact AMR Knoxville at 865-305-DRUG (3784) for more study details.
We have a Flu vaccine study coming up! If you’d like to see if you qualify and get on the waiting list, call us at 865-305-3784 or fill out the volunteer form below.
Frequently Asked Questions
In Phase I trials, researchers test an experimental drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase II trials, the experimental study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase III trials, the experimental study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the experimental drug or treatment to be used safely.
A protocol is a study plan on which all clinical trials are based. The plan is carefully designed to safeguard the health of the participants as well as answer specific research questions. A protocol describes what types of people may participate in the trial; the schedule of tests, procedures, medications, and dosages; and the length of the study. While in a clinical trial, participants following a protocol are seen regularly by the research staff to monitor their health and to determine the safety and effectiveness of their treatment.
Clinical trials that are well-designed and well-executed are the best approach for eligible participants to:
Play an active role in their own health care.
Gain access to new research treatments before they are widely available.
Obtain expert medical care at leading healthcare facilities during the trial.
Help others by contributing to medical research.
Risks
There are risks to clinical trials.
There may be unpleasant, serious or even life-threatening side effects to experimental treatment.
The experimental treatment may not be effective for the participant.
The protocol may require more of their time and attention than would a non-protocol treatment, including trips to the study site, more treatments, hospital stays or complex dosage requirements.
Some clinical trials involve more tests and doctor visits than the participant would normally have for an illness or condition. For all types of trials, the participant works with a research team. Clinical trial participation is most successful when the protocol is carefully followed and there is frequent contact with the research staff.
All clinical trials have guidelines about who can participate. Using inclusion/exclusion criteria is an important principle of medical research that helps to produce reliable results. The factors that allow someone to participate in a clinical trial are called “inclusion criteria” and those that disallow someone from participating are called “exclusion criteria”. These criteria are based on such factors as age, gender, the type and stage of a disease, previous treatment history, and other medical conditions. Before joining a clinical trial, a participant must qualify for the study. Some research studies seek participants with illnesses or conditions to be studied in the clinical trial, while others need healthy participants. It is important to note that inclusion and exclusion criteria are not used to reject people personally. Instead, the criteria are used to identify appropriate participants and keep them safe. The criteria help ensure that researchers will be able to answer the questions they plan to study
Participants in clinical trials can play a more active role in their own health care, gain access to new research treatments before they are widely available, and help others by contributing to medical research.
Although there are many definitions of clinical trials, they are generally considered to be biomedical or health-related research studies in human beings that follow a predefined protocol. ClinicalTrials.gov includes both interventional and observational types of studies. Interventional studies are those in which the research subjects are assigned by the investigator to a treatment or other intervention, and their outcomes are measured. Observational studies are those in which individuals are observed and their outcomes are measured by the investigators.
Volunteer Form
By volunteering for clinical studies, you authorize AMR to store your personal information on file. In accordance with HIPAA regulations, AMR will never share your information with anyone.
Respiratory Syncytial Virus
It is estimated that more than 177,000 older adults are hospitalized and 14,000 of them die in the US due to RSV infections per year. In 2018, more elder Americans died from RSV infection than the common flu.
To learn more, call our enrollment line:
Refer-A-Friend
Earn extra cash* by recommending a friend to us and receive up to $100 for each friend you refer!
Read Important Instructions
* Some restrictions apply. Not all studies are eligible for the Refer-A-Friend program. Ask an AMR representative for details.
Refer-A-Friend
Step 1
Fill out the Refer-A-Friend form. You can download the form here or pick one up at one of our offices. The referrer (you) must fill out the form.
Step 2
Your friend or family member brings the completed referral form to CRC on their first visit to our office and gives it to a staff member upon checking in.
Step 3
If your referral qualifies for and completes all visits for the study, you (the referrer) will earn $100 upon study completion.